Nerolidol (CAS N° 7212-44-4)​

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Nerolidol

3,7,11-trimethyldodeca-1,6,10-trien-3-ol ; 3-hydroxy-3,7,11-trimethyl-1,6,10-dodecatriene ; Melaleucol ; Methyl vinyl homogeranyl carbinol ; 3,7,11- trimethyl-1,6,10-dodecatrien-3-ol

Nerolidol (CAS N° 7212-44-4)​

Photo credits: ScenTree SAS

Company Ingredient Name ID Comments Naturality Certifications Purity Latin name Treated part Geographical origin MOQ
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Nerolidol 30034996 Visit website Je me procure cet ingrédient Molecule - - - - -

Nerolidol

ID : 30034996

Certifications :

Information Générales

General Presentation

  • CAS N° : 7212-44-4

  • EINECS number : 230-597-5

  • FEMA number : 2772

  • FLAVIS number : 02.018

  • JECFA number : 1646

  • Appearance : Colorless liquid

  • Density : 0,874

  • Volatility : Head

  • Price Range : €€

Physico-chemical properties

  • Molecular formula : C15H26O

  • Molecular Weight : 222,37 g/mol

  • Log P : 5

  • Fusion Point : Donnée indisponible.

  • Boiling Point : 276°C

  • Detection Threshold : De l'ordre de 10 ppb à 10 ppm (0,0001%) selon les personnes

  • Optical rotation : Donnée indisponible

  • Vapor pressure : Donnée indisponible

  • Refractive Index @20°C : Donnée indisponible

  • Acid Value : Donnée indisponible.

  • Flash Point : 125°C

Utilisation

Uses

Uses in perfumery :

Nerolidol is used in all types of perfumery for orange, rose, honeysuckle and lily of the valley notes. Useful in citrus and woody-vanillic accords, to give an airy side and make the link between those two facets.

Year of discovery :

Discovered in 1923

Natural availability :

Dextrorotatory trans-Nerolidol is the major compound of cabreuva (84%), a shrub of Paraguay. This same dextrorotatory nerolidol is isolated from Dalbergia parviflora, an Asian liana.

Isomerism :

Nerolidol exists as two pairs of enantiomers, as it has an asymmetric carbon and a double bond that gives rise to two diastereoisomers. Synthetic Nerolidol is however a mixture of all these isomers. All have a similar smell, but they do not have the same physicochemical properties.

Synthesis precursor :

Nerolidol can be a precursor to the synthesis of other terpenes, for example by a Diels-Alder reaction. It is also a precursor for the synthesis of Farnesol, following an isomerization process.

Synthesis route :

Nerolidol is a sesquiterpene, often associated with Linalool, whose synthesis starts from this last compound. Linalool is converted to geranylacetone by reaction with Ethyl Acetoacetate, for example. A condensation of the obtained ketone with acetylene, followed by a Lindlar palladium catalysed hydrogenation allows to obtain Nerolidol.

Utilisation

Regulations & IFRA

Allergens :

This ingredient does not contain any allergen.

IFRA 51th :

This ingredient is not restricted for the 51th amendment

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