Ambrinol

Other comments :

Ambrinol can be compared with Ambrein or DihydroBeta-Ionone, as it is used to reproduce the smell of natural Ambergris.

Stability :

Stable in perfumes and various functionnal bases.

Uses in perfumery :

Ambrinol is used to reproduce the natural Ambergris smell, bringing an animalic, sensual and ambery note, with a fixative effect.

Year of discovery :

Data not available.

Isomerism :

Ambrinol frequently used in perfumes is Alpha-Ambrinol. Beta-Ambrinol also exists, but is much less used. On the other hand, Ambrinol has one asymmetric carbon, giving birth to two possible enantiomers for this molecule. It is anyway a mixture of these isomers that is used in perfumery. Eventually, Ambrinol also is a constitutional isomer of DihydroBeta-ionone, also prepared from Beta-Ionone.

Synthesis precursor :

Ambrinol is not a precursor for the synthesis of another material used in perfumery.

Natural availability :

Ambrinol is one of the components of Ambergris, previously used for its sensual and animalic notes, and extracted as a tincture in alcohol. Then, only synthetic Ambrinol is used for perfumery.

Synthesis route :

Ambrinol can be synthesized thanks to Beta-Ionone. This molecule can undergo thermolysis (chemical decomposition under the effect of heat), bringing dehydroambrinol. Hydrogenation in methanol, in the presence of Raney nickel catalysor leads to Ambrinol.