Manzanate®

Other comments :

Manzanate® is one of the commercial keys of modern perfumery. At the right dosage, it makes the perfume more addictive, wheither it is a functional or fine fragrance. Among these keys, Verdox®, Styrallyle acetate® and Ambroxan® can also be quoted.

Stability :

Only stable in Fabric conditioner, APC and shampoo bases. Particularly unstable in liquid fabric detergent and liquid bleach

Uses in perfumery :

Manzanate® is a key molecule in masculine perfumes. It is often used in small quantities to bring a strong fruity and addictive impact from the top note of the perfume, with a metallic and green note. Also used in apple, pineapple, exotic fruits and yellow fruits notes, to bring a heady and green effect.

Year of discovery :

1974

Isomerism :

Manzanate® has one asymmetric carbon in its strcture. (R)-2-methylpentanoate and (S)-2-methylpentanoate both exist. Manzanate® is a mixture of these two enantiomers. They are not used separately. On the other hand, Ethyl Caproate is a positional isomer of Manzanate®. Its smell is less elegant and closer to ripe pineapple, less green.

Synthesis precursor :

Manzanate® is not a precursor for the synthesis of another compound used in perfumes.

Natural availability :

Manzanate® is not reported as found in nature.

Synthesis route :

Manzanate® can be synthesized by an esterification reaction between 2-methylpentanoic acid and ethanol. This reaction can be catalyzed by the presence of a strong acid in a low quantity as concentrated sulfuric acid, to enhance the reaction yield. The use of chloro-2-methylpentanoic acid can also be a help.