Pharaone®

Other comments :

Synergy with Stemone® in a 1:9 ratio of use, to create a tomato leaf effect.

Stability :

Stable in perfumes and in diverse functional bases, except in very acidic bases (detergents) and strong alkaline bases (liquid bleach).

Uses in perfumery :

Pharaone® is useful as a green booster from the top note, with a fruity effect.

Year of discovery :

1999

Isomerism :

Pharaone® is a constitutional isomer of Alpha-Ionone, Beta-Ionone, Alpha-Damascone® and Beta-Damascone®, but has a much fruitier smell, close to pineapple.

Synthesis precursor :

Pharaone® is not used for the synthesis of another molecule of olfactive interest.

Natural availability :

Pharaone® does not exist on a natural state. Thus, it can't be used as extracted from a plant.

Synthesis route :

The Pharaone® synthesis involves a few steps, starting from Cyclohexyl Acetaldehyde. The first step is a Mannich reaction involving formaldehyde in an acidic medium on the basic reagent, to add an alpha-positioned insaturated ramification, according to its cycle. The second step is a Grignard reaction, between the obtained intermediate product and an organomagnesian as butenylmagnesium bromide, to convert the aldehyde into an alcohol and add a carbon chain to the molecule. The last step is an oxydation that can be carried out using manganese oxide, converting the alcohol into a ketone. This step leads to Pharaone®.